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The ribosome modulates folding inside the ribosomal exit tunnel

Proteins commonly fold co-translationally at the ribosome, while the nascent chain emerges from the ribosomal exit tunnel. Protein domains that are sufficiently small can even fold while still located inside the tunnel. However, the effect of the tunnel on the folding dynamics of these domains is no...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Commun Biol
Main Authors: Wruck, Florian, Tian, Pengfei, Kudva, Renuka, Best, Robert B., von Heijne, Gunnar, Tans, Sander J., Katranidis, Alexandros
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100117/
https://ncbi.nlm.nih.gov/pubmed/33953328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02055-8
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