Transmembrane but not soluble helices fold inside the ribosome tunnel

Integral membrane proteins are assembled into the ER membrane via a continuous ribosome-translocon channel. The hydrophobicity and thickness of the core of the membrane bilayer leads to the expectation that transmembrane (TM) segments minimize the cost of harbouring polar polypeptide backbones by ad...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Bañó-Polo, Manuel, Baeza-Delgado, Carlos, Tamborero, Silvia, Hazel, Anthony, Grau, Brayan, Nilsson, IngMarie, Whitley, Paul, Gumbart, James C., von Heijne, Gunnar, Mingarro, Ismael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286305/
https://ncbi.nlm.nih.gov/pubmed/30531789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07554-7
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