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Molecular code for protein insertion in the endoplasmic reticulum membrane is similar for N(in)–C(out) and N(out)–C(in) transmembrane helices

Transmembrane α-helices in integral membrane proteins can have two orientations in the membrane: N(in)–C(out) or N(out)–C(in). Previous studies of model N(out)–C(in) transmembrane segment have led to a detailed, quantitative picture of the “molecular code” that relates amino acid sequence to membran...

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Autors principals: Lundin, Carolina, Kim, Hyun, Nilsson, IngMarie, White, Stephen H., von Heijne, Gunnar
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572976/
https://ncbi.nlm.nih.gov/pubmed/18840693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804842105
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