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A functional connection between translation elongation and protein folding at the ribosome exit tunnel in Saccharomyces cerevisiae

Proteostasis needs to be tightly controlled to meet the cellular demand for correctly de novo folded proteins and to avoid protein aggregation. While a coupling between translation rate and co-translational folding, likely involving an interplay between the ribosome and its associated chaperones, cl...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Rodríguez-Galán, Olga, García-Gómez, Juan J, Rosado, Iván V, Wei, Wu, Méndez-Godoy, Alfonso, Pillet, Benjamin, Alekseenko, Alisa, Steinmetz, Lars M, Pelechano, Vicent, Kressler, Dieter, de la Cruz, Jesús
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797049/
https://ncbi.nlm.nih.gov/pubmed/33330942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1200
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