A functional connection between translation elongation and protein folding at the ribosome exit tunnel in Saccharomyces cerevisiae

Proteostasis needs to be tightly controlled to meet the cellular demand for correctly de novo folded proteins and to avoid protein aggregation. While a coupling between translation rate and co-translational folding, likely involving an interplay between the ribosome and its associated chaperones, cl...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Rodríguez-Galán, Olga, García-Gómez, Juan J, Rosado, Iván V, Wei, Wu, Méndez-Godoy, Alfonso, Pillet, Benjamin, Alekseenko, Alisa, Steinmetz, Lars M, Pelechano, Vicent, Kressler, Dieter, de la Cruz, Jesús
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Gene regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797049/
https://ncbi.nlm.nih.gov/pubmed/33330942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1200
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