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Using an Interaction Parameter in Model-Based Phase I Trials for Combination Treatments? A Simulation Study
There is growing interest in Phase I dose-finding studies studying several doses of more than one agent simultaneously. A number of combination dose-finding designs were recently proposed to guide escalation/de-escalation decisions during the trials. The majority of these proposals are model-based:...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Int J Environ Res Public Health |
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| Prif Awduron: | , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
MDPI
2021
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7796482/ https://ncbi.nlm.nih.gov/pubmed/33466469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijerph18010345 |
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