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A surface-free design for phase I dual-agent combination trials
In oncology, there is a growing number of therapies given in combination. Recently, several dose-finding designs for Phase I dose-escalation trials for combinations were proposed. The majority of novel designs use a pre-specified parametric model restricting the search of the target combination to a...
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| Publicado no: | Stat Methods Med Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7612168/ https://ncbi.nlm.nih.gov/pubmed/32338145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280220919450 |
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