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A dose-finding design for dual-agent trials with patient-specific doses for one agent with application to an opiate detoxification trial

There is a growing interest in early phase dose-finding clinical trials studying combinations of several treatments. While the majority of dose finding designs for such setting were proposed for oncology trials, the corresponding designs are also essential in other therapeutic areas. Furthermore, th...

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Detalhes bibliográficos
Publicado no:Pharm Stat
Main Authors: Mozgunov, Pavel, Cro, Suzie, Lingford-Hughes, Anne, Paterson, Louise M., Jaki, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612599/
https://ncbi.nlm.nih.gov/pubmed/34891221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pst.2181
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