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Early phase clinical trials in oncology: realising the potential of seamless designs

BACKGROUND: The pharmaceutical industry’s productivity has been declining over the last two decades and high attrition rates and reduced regulatory approvals are being seen. The development of oncology drugs is particularly challenging with low rates of approval for novel treatments when compared wi...

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Bibliographische Detailangaben
Veröffentlicht in:Eur J Cancer
Hauptverfasser: Jaki, Thomas, Burdon, Abigail, Chen, Xijin, Mozgunov, Pavel, Zheng, Haiyan, Baird, Richard
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2023
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614750/
https://ncbi.nlm.nih.gov/pubmed/37301716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2023.05.005
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