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Effects of blocking mGluR5 on primate dorsolateral prefrontal cortical neuronal firing and working memory performance
RATIONALE: Metabotropic glutamate type 5 receptor (mGluR5) antagonists are under development for treating cognitive disorders such as Fragile X syndrome and Alzheimer’s disease, largely based on success in mouse models, where post-synaptic mGluR5 stimulation weakens synaptic functions in hippocampus...
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| 出版年: | Psychopharmacology (Berl) |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer Berlin Heidelberg
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7794104/ https://ncbi.nlm.nih.gov/pubmed/32939596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-020-05661-2 |
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