mGluR2/3 mechanisms in primate dorsolateral prefrontal cortex: evidence for both presynaptic and postsynaptic actions

Cognitive deficits in psychiatric and age-related disorders generally involve dysfunction of the dorsolateral prefrontal cortex (dlPFC), but there are few treatments for these debilitating symptoms. Group II metabotropic glutamate receptors (mGluR2/3), which couple to Gi/Go, have been a focus of the...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Jin, L E, Wang, M, Yang, S-T, Yang, Y, Galvin, V C, Lightbourne, T C, Ottenheimer, D, Zhong, Q, Stein, J, Raja, A, Paspalas, C D, Arnsten, A F T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5298940/
https://ncbi.nlm.nih.gov/pubmed/27502475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.129
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