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mGluR2 versus mGluR3 Metabotropic Glutamate Receptors in Primate Dorsolateral Prefrontal Cortex: Postsynaptic mGluR3 Strengthen Working Memory Networks

The newly evolved circuits in layer III of primate dorsolateral prefrontal cortex (dlPFC) generate the neural representations that subserve working memory. These circuits are weakened by increased cAMP-K(+) channel signaling, and are a focus of pathology in schizophrenia, aging, and Alzheimer's...

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Detalhes bibliográficos
Publicado no:Cereb Cortex
Main Authors: Jin, Lu E, Wang, Min, Galvin, Veronica C, Lightbourne, Taber C, Conn, Peter Jeffrey, Arnsten, Amy F T, Paspalas, Constantinos D
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974790/
https://ncbi.nlm.nih.gov/pubmed/28108498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhx005
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