mGluR2 versus mGluR3 Metabotropic Glutamate Receptors in Primate Dorsolateral Prefrontal Cortex: Postsynaptic mGluR3 Strengthen Working Memory Networks

The newly evolved circuits in layer III of primate dorsolateral prefrontal cortex (dlPFC) generate the neural representations that subserve working memory. These circuits are weakened by increased cAMP-K(+) channel signaling, and are a focus of pathology in schizophrenia, aging, and Alzheimer's...

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Bibliografiske detaljer
Udgivet i:Cereb Cortex
Main Authors: Jin, Lu E, Wang, Min, Galvin, Veronica C, Lightbourne, Taber C, Conn, Peter Jeffrey, Arnsten, Amy F T, Paspalas, Constantinos D
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974790/
https://ncbi.nlm.nih.gov/pubmed/28108498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhx005
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