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Global Genome Demethylation Causes Transcription-Associated DNA Double Strand Breaks in HPV-Associated Head and Neck Cancer Cells
SIMPLE SUMMARY: High levels of global genome methylation in HPV-associated head and neck cancer prompted us to explore demethylation as a potential treatment by determining mechanisms of its toxicity in HPV-positive head and neck cancer cells. Previously, we reported that demethylating drug 5-azaC s...
שמור ב:
| הוצא לאור ב: | Cancers (Basel) |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
MDPI
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7793113/ https://ncbi.nlm.nih.gov/pubmed/33374558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13010021 |
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