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Reverse Phase Protein Array profiling of oropharyngeal cancer and significance of PIK3CA mutations in HPV-associated head and neck cancer

PURPOSE: HPV-associated (HPV+) oropharyngeal squamous cell carcinomas (OPSCC) have different molecular and biological characteristics and clinical behavior compared to HPV-negative (HPV−) OPSCC. PIK3CA mutations are more common in HPV(+)OPSCC. To define molecular differences and tumor subsets, prote...

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Autors principals: Sewell, Andrew, Brown, Brandee, Biktasova, Asel, Mills, Gordon B., Lu, Yiling, Tyson, Darren R., Issaeva, Natalia, Yarbrough, Wendell G.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027970/
https://ncbi.nlm.nih.gov/pubmed/24599934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-2585
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