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Selective antitumor activity of roscovitine in head and neck cancer

Radiation and chemotherapy that are commonly used to treat human cancers damage cellular DNA. DNA damage appears to be more toxic to cancer cells than normal cells, most likely due to deregulated checkpoint activation and/or deficiency in DNA repair pathways that are characteristics of many tumors....

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gary, Cyril, Hajek, Michael, Biktasova, Asel, Bellinger, Gary, Yarbrough, Wendell G., Issaeva, Natalia
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122414/
https://ncbi.nlm.nih.gov/pubmed/27233076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9560
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