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Selective antitumor activity of roscovitine in head and neck cancer
Radiation and chemotherapy that are commonly used to treat human cancers damage cellular DNA. DNA damage appears to be more toxic to cancer cells than normal cells, most likely due to deregulated checkpoint activation and/or deficiency in DNA repair pathways that are characteristics of many tumors....
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| Veröffentlicht in: | Oncotarget |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5122414/ https://ncbi.nlm.nih.gov/pubmed/27233076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9560 |
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