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Selective antitumor activity of roscovitine in head and neck cancer

Radiation and chemotherapy that are commonly used to treat human cancers damage cellular DNA. DNA damage appears to be more toxic to cancer cells than normal cells, most likely due to deregulated checkpoint activation and/or deficiency in DNA repair pathways that are characteristics of many tumors....

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Gary, Cyril, Hajek, Michael, Biktasova, Asel, Bellinger, Gary, Yarbrough, Wendell G., Issaeva, Natalia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122414/
https://ncbi.nlm.nih.gov/pubmed/27233076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9560
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