NSD1 mutations by HPV status in head and neck cancer: differences in survival and response to DNA-damaging agents

BACKGROUND: Compared to HPV-negative head and neck squamous cell carcinomas (HNSCCs), HPV-positive HNSCCs are associated with a favorable prognosis in part due to their improved treatment sensitivity. Inactivating mutations in NSD1 were shown to be a favorable prognostic biomarker in laryngeal cance...

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Bibliographic Details
Published in:Cancers Head Neck
Main Authors: Pan, Cassie, Izreig, Said, Yarbrough, Wendell G., Issaeva, Natalia
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613249/
https://ncbi.nlm.nih.gov/pubmed/31321084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41199-019-0042-3
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