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Pharmacological Inhibition of mTORC2 Reduces Migration and Metastasis in Melanoma

Despite recent advances in therapy, liver metastasis from melanoma is still associated with poor prognosis. Although targeting the mTOR signaling pathway exerts potent anti-tumor activity, little is known about specific mTORC2 inhibition regarding liver metastasis. Using the novel mTORC2 specific in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Guenzle, Jessica, Akasaka, Harue, Joechle, Katharina, Reichardt, Wilfried, Venkatasamy, Aina, Hoeppner, Jens, Hellerbrand, Claus, Fichtner-Feigl, Stefan, Lang, Sven A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792954/
https://ncbi.nlm.nih.gov/pubmed/33375117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010030
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