Estrogen receptor-α prevents right ventricular diastolic dysfunction and fibrosis in female rats

Although women are more susceptible to pulmonary arterial hypertension (PAH) than men, their right ventricular (RV) function is better preserved. Estrogen receptor-α (ERα) has been identified as a likely mediator for estrogen protection in the RV. However, the role of ERα in preserving RV function a...

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Udgivet i:Am J Physiol Heart Circ Physiol
Main Authors: Cheng, Tik-Chee, Philip, Jennifer L., Tabima, Diana M., Kumari, Santosh, Yakubov, Bakhtiyor, Frump, Andrea L., Hacker, Timothy A., Bellofiore, Alessandro, Li, Rongbo, Sun, Xin, Goss, Kara N., Lahm, Tim, Chesler, Naomi C.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792707/
https://ncbi.nlm.nih.gov/pubmed/33064565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00247.2020
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