Estrogen receptor-α prevents right ventricular diastolic dysfunction and fibrosis in female rats

Although women are more susceptible to pulmonary arterial hypertension (PAH) than men, their right ventricular (RV) function is better preserved. Estrogen receptor-α (ERα) has been identified as a likely mediator for estrogen protection in the RV. However, the role of ERα in preserving RV function a...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Cheng, Tik-Chee, Philip, Jennifer L., Tabima, Diana M., Kumari, Santosh, Yakubov, Bakhtiyor, Frump, Andrea L., Hacker, Timothy A., Bellofiore, Alessandro, Li, Rongbo, Sun, Xin, Goss, Kara N., Lahm, Tim, Chesler, Naomi C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792707/
https://ncbi.nlm.nih.gov/pubmed/33064565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00247.2020
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