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Estrogen receptor-α prevents right ventricular diastolic dysfunction and fibrosis in female rats

Although women are more susceptible to pulmonary arterial hypertension (PAH) than men, their right ventricular (RV) function is better preserved. Estrogen receptor-α (ERα) has been identified as a likely mediator for estrogen protection in the RV. However, the role of ERα in preserving RV function a...

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Pubblicato in:Am J Physiol Heart Circ Physiol
Autori principali: Cheng, Tik-Chee, Philip, Jennifer L., Tabima, Diana M., Kumari, Santosh, Yakubov, Bakhtiyor, Frump, Andrea L., Hacker, Timothy A., Bellofiore, Alessandro, Li, Rongbo, Sun, Xin, Goss, Kara N., Lahm, Tim, Chesler, Naomi C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792707/
https://ncbi.nlm.nih.gov/pubmed/33064565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00247.2020
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