Antibody Co-Administration Can Improve Systemic and Local Distribution of Antibody Drug Conjugates to Increase In Vivo Efficacy

Several antibody-drug conjugates (ADCs) showing strong clinical responses in solid tumors target high expression antigens (HER2, TROP2, Nectin-4, and folate receptor alpha/FRα). Highly expressed tumor antigens often have significant low-level expression in normal tissues, resulting in the potential...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Ponte, Jose F., Lanieri, Leanne, Khera, Eshita, Laleau, Rassol, Ab, Olga, Espelin, Christopher, Kohli, Neeraj, Matin, Bahar, Setiady, Yulius, Miller, Michael L., Keating, Thomas A., Chari, Ravi, Pinkas, Jan, Gregory, Richard, Thurber, Greg M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790875/
https://ncbi.nlm.nih.gov/pubmed/33177153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-20-0451
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados