Mirvetuximab Soravtansine (IMGN853), a Folate Receptor Alpha–Targeting Antibody-Drug Conjugate, Potentiates the Activity of Standard of Care Therapeutics in Ovarian Cancer Models()...

Por Ponte, Jose F., Ab, Olga, Lanieri, Leanne, Lee, Jenny, Coccia, Jennifer, Bartle, Laura M., Themeles, Marian, Zhou, Yinghui, Pinkas, Jan, Ruiz-Soto, Rodrigo
Publicado no Neoplasia (2016)

Antibody Co-Administration Can Improve Systemic and Local Distribution of Antibody Drug Conjugates to Increase In Vivo Efficacy

Por Ponte, Jose F., Lanieri, Leanne, Khera, Eshita, Laleau, Rassol, Ab, Olga, Espelin, Christopher, Kohli, Neeraj, Matin, Bahar, Setiady, Yulius, Miller, Michael L., Keating, Thomas A., Chari, Ravi, Pinkas, Jan, Gregory, Richard, Thurber, Greg M.
Publicado no Mol Cancer Ther (2020)

A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells

Por Kovtun, Yelena, Jones, Gregory E., Adams, Sharlene, Harvey, Lauren, Audette, Charlene A., Wilhelm, Alan, Bai, Chen, Rui, Lingyun, Laleau, Rassol, Liu, Fenghua, Ab, Olga, Setiady, Yulius, Yoder, Nicholas C., Goldmacher, Victor S., Chari, Ravi V. J., Pinkas, Jan, Chittenden, Thomas
Publicado no Blood Adv (2018)

Synthesis of Highly Potent N-10 Amino-Linked DNA-Alkylating Indolinobenzodiazepine Antibody–Drug Conjugates (ADCs)

Por Archer, Katie E., Reid, Emily E., Shizuka, Manami, Woods, James, Harris, Luke, Maloney, Erin K., Bartle, Laura M., Ab, Olga, Wilhelm, Alan, Setiady, Yulius, Ponte, Jose F., Singh, Rajeeva, Keating, Thomas A., Chari, Ravi V. J., Miller, Michael L.
Publicado no ACS Med Chem Lett (2019)

Peptide-Cleavable Self-immolative Maytansinoid Antibody–Drug Conjugates Designed To Provide Improved Bystander Killing

Por Costoplus, Juliet A., Veale, Karen H., Qiu, Qifeng, Ponte, Jose F., Lanieri, Leanne, Setiady, Yulius, Dong, Ling, Skaletskaya, Anna, Bartle, Laura M., Salomon, Paulin, Wu, Rui, Maloney, Erin K., Kovtun, Yelena V., Ab, Olga, Lai, Kate, Chari, Ravi V. J., Widdison, Wayne C.
Publicado no ACS Med Chem Lett (2019)

Effect of Linker Stereochemistry on the Activity of Indolinobenzodiazepine Containing Antibody–Drug Conjugates (ADCs)

Por Reid, Emily E., Archer, Katie E., Shizuka, Manami, Wilhelm, Alan, Yoder, Nicholas C., Bai, Chen, Fishkin, Nathan E., Harris, Luke, Maloney, Erin K., Salomon, Paulin, Hong, Erica, Wu, Rui, Ab, Olga, Jin, Shan, Lai, Katharine C., Sikka, Surina, Chari, Ravi V. J., Miller, Michael L.
Publicado no ACS Med Chem Lett (2019)

Synthesis and Evaluation of Camptothecin Antibody–Drug Conjugates

Por Li, Wei, Veale, Karen H., Qiu, Qifeng, Sinkevicius, Kerstin W., Maloney, Erin K., Costoplus, Juliet A., Lau, Janet, Evans, Helen L., Setiady, Yulius, Ab, Olga, Abbott, Stephen M., Lee, Jenny, Wisitpitthaya, Somsinee, Skaletskaya, Anna, Wang, Lintao, Keating, Thomas A., Chari, Ravi V. J., Widdison, Wayne C.
Publicado no ACS Med Chem Lett (2019)