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Ribociclib mitigates cisplatin-associated kidney injury through retinoblastoma-1 dependent mechanisms
Aberrant cell cycle activation is a hallmark of carcinogenesis. Recently three cell cycle targeting cyclin-dependent kinase 4/6 (CDK4/6) inhibitors have been approved for the treatment of metastatic breast cancer. CDK4/6 inhibitors suppress proliferation through inhibition of CDK4/6-dependent retino...
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| Publicado no: | Biochem Pharmacol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7789910/ https://ncbi.nlm.nih.gov/pubmed/32229099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2020.113939 |
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