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Mechanisms of Cisplatin-Induced Acute Kidney Injury: Pathological Mechanisms, Pharmacological Interventions, and Genetic Mitigations

SIMPLE SUMMARY: Nephrotoxicity is the dose-limiting factor of cisplatin treatment. Nephrotoxicity is characterized by reduced kidney function. Although an often-reversible condition, effects are notably seen years after treatment with cisplatin has ceased. It has an extensive pathophysiological map....

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: McSweeney, Kristen Renee, Gadanec, Laura Kate, Qaradakhi, Tawar, Ali, Benazir Ashiana, Zulli, Anthony, Apostolopoulos, Vasso
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8036620/
https://ncbi.nlm.nih.gov/pubmed/33805488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13071572
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