Modulation of arousal and sleep/wake architecture by M(1) PAM VU0453595 across young and aged rodents and nonhuman primates

Degeneration of basal forebrain cholinergic circuitry represents an early event in the development of Alzheimer’s disease (AD). These alterations in central cholinergic function are associated with disruptions in arousal, sleep/wake architecture, and cognition. Changes in sleep/wake architecture are...

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Publicado no:Neuropsychopharmacology
Main Authors: Gould, Robert W., Russell, Jason K., Nedelcovych, Michael T., Bubser, Michael, Blobaum, Anna L., Bridges, Thomas M., Newhouse, Paul A., Lindsley, Craig W., Conn, P. Jeffrey, Nader, Michael A., Jones, Carrie K.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784923/
https://ncbi.nlm.nih.gov/pubmed/32868847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-020-00812-7
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