Cognitive enhancement and antipsychotic-like activity following repeated dosing with the selective M(4) PAM VU0467154

Although selective activation of the M(1) muscarinic acetylcholine receptor (mAChR) subtype has been shown to improve cognitive function in animal models of neuropsychiatric disorders, recent evidence suggests that enhancing M(4) mAChR function can also improve memory performance. Positive allosteri...

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Bibliografske podrobnosti
izdano v:Neuropharmacology
Main Authors: Gould, Robert W., Grannan, Michael D., Gunter, Barak W., Ball, Jacob, Bubser, Michael, Bridges, Thomas M., Wess, Jurgen, Wood, Michael W., Brandon, Nicholas J., Duggan, Mark E., Niswender, Colleen M., Lindsley, Craig W., Conn, P. Jeffrey, Jones, Carrie K.
Format: Artigo
Jezik:Inglês
Izdano: 2017
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756753/
https://ncbi.nlm.nih.gov/pubmed/28729220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.07.013
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