Prefrontal Cortex-Mediated Impairments in a Genetic Model of NMDA Receptor Hypofunction Are Reversed by the Novel M(1) PAM VU6004256

Abnormalities in the signaling of the N-methyl-D-aspartate subtype of the glutamate receptor (NMDAR) within cortical and limbic brain regions are thought to underlie many of the complex cognitive and affective symptoms observed in individuals with schizophrenia. The M(1) muscarinic acetylcholine rec...

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Опубликовано в: :ACS Chem Neurosci
Главные авторы: Grannan, Michael D., Mielnik, Catharine A., Moran, Sean P., Gould, Robert W., Ball, Jacob, Lu, Zhuoyan, Bubser, Michael, Ramsey, Amy J., Abe, Masahito, Cho, Hyekyung P., Nance, Kellie D., Blobaum, Anna L., Niswender, Colleen M., Conn, P. Jeffrey, Lindsley, Craig W., Jones, Carrie K.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5231396/
https://ncbi.nlm.nih.gov/pubmed/27617634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.6b00230
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