Prefrontal Cortex-Mediated Impairments in a Genetic Model of NMDA Receptor Hypofunction Are Reversed by the Novel M(1) PAM VU6004256

Abnormalities in the signaling of the N-methyl-D-aspartate subtype of the glutamate receptor (NMDAR) within cortical and limbic brain regions are thought to underlie many of the complex cognitive and affective symptoms observed in individuals with schizophrenia. The M(1) muscarinic acetylcholine rec...

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Bibliografske podrobnosti
izdano v:ACS Chem Neurosci
Main Authors: Grannan, Michael D., Mielnik, Catharine A., Moran, Sean P., Gould, Robert W., Ball, Jacob, Lu, Zhuoyan, Bubser, Michael, Ramsey, Amy J., Abe, Masahito, Cho, Hyekyung P., Nance, Kellie D., Blobaum, Anna L., Niswender, Colleen M., Conn, P. Jeffrey, Lindsley, Craig W., Jones, Carrie K.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5231396/
https://ncbi.nlm.nih.gov/pubmed/27617634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.6b00230
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