Double somatic mismatch repair gene pathogenic variants as common as Lynch syndrome among endometrial cancer patients

OBJECTIVE. Lynch syndrome is the most common cause of inherited endometrial cancer, attributable to germline pathogenic variants (PV) in mismatch repair (MMR) genes. Tumor microsatellite instability (MSI-high) and MMR IHC abnormalities are characteristics of Lynch syndrome. Double somatic MMR gene P...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Gynecol Oncol
Main Authors: Hampel, Heather, Pearlman, Rachel, de la Chapelle, Albert, Pritchard, Colin C., Zhao, Weiqiang, Jones, Dan, Yilmaz, Ahmet, Chen, Wei, Frankel, Wendy L., Suarez, Adrian A., Cosgrove, Casey, Backes, Floor, Copeland, Larry, Fowler, Jeffrey, O'Malley, David, Salani, Ritu, McElroy, Joseph P., Stanich, Peter P., Goodfellow, Paul, Cohn, David E.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7783191/
https://ncbi.nlm.nih.gov/pubmed/33393477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2020.10.012
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki