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Unexpected Expression of Mismatch Repair Protein Is More Commonly Seen with Pathogenic Missense than Other Mutations in Lynch Syndrome
It has been observed that some colorectal cancer patients due to germline or double somatic pathogenic variants in the mismatch repair (MMR) genes may have intact protein expression observed in their tumors by immunohistochemistry (IHC). This has been speculated to occur more frequently in Lynch Syn...
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| Publicado no: | Hum Pathol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7664304/ https://ncbi.nlm.nih.gov/pubmed/32652087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humpath.2020.07.001 |
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