טוען...
Clinical Characteristics of Colorectal Cancer Patients with Double Somatic Mismatch Repair Mutations Compared to Lynch Syndrome
BACKGROUND: Colorectal cancer (CRC) patients with mismatch repair-deficient (dMMR) tumors without MLH1 methylation or germline MMR pathogenic variants (PVs) were previously thought to have Lynch syndrome (LS). It’s now appreciated that they can have double somatic (DS) MMR PVs. We explored clinical...
שמור ב:
| הוצא לאור ב: | J Med Genet |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6748629/ https://ncbi.nlm.nih.gov/pubmed/30877237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2018-105698 |
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