Cyclophosphamide Enhances Cancer Antibody Immunotherapy in the Resistant Bone Marrow Niche by Modulating Macrophage FcγR Expression

Therapy-resistant microenvironments represent a major barrier toward effective elimination of disseminated cancer. Many hematologic and solid tumors are resistant to therapeutic antibodies in the bone marrow (BM), but not in the periphery (e.g., spleen). We previously showed that cyclophosphamide (C...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Immunol Res
Egile Nagusiak: Roghanian, Ali, Hu, Guangan, Fraser, Christopher, Singh, Maneesh, Foxall, Russell B., Meyer, Matthew J., Lees, Emma, Huet, Heather, Glennie, Martin J., Beers, Stephen A., Lim, Sean H., Ashton-Key, Margaret, Thirdborough, Stephen M., Cragg, Mark S., Chen, Jianzhu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780711/
https://ncbi.nlm.nih.gov/pubmed/31451483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0835
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