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Resistance is futile: Targeting the inhibitory FcγRIIB (CD32B) to maximize immunotherapy

Monoclonal antibodies (mAb) are central to the treatment of several types of malignancy. However, these reagents are subject to particular types of resistance. Several resistance mechanisms are regulated by the inhibitory FcγRIIB. We recently developed mAbs to block FcγRIIB and provided in vivo proo...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Roghanian, Ali, Cragg, Mark S., Frendéus, Björn
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801439/
https://ncbi.nlm.nih.gov/pubmed/27057434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1069939
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