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Resistance is futile: Targeting the inhibitory FcγRIIB (CD32B) to maximize immunotherapy

Monoclonal antibodies (mAb) are central to the treatment of several types of malignancy. However, these reagents are subject to particular types of resistance. Several resistance mechanisms are regulated by the inhibitory FcγRIIB. We recently developed mAbs to block FcγRIIB and provided in vivo proo...

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Publicat a:Oncoimmunology
Autors principals: Roghanian, Ali, Cragg, Mark S., Frendéus, Björn
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801439/
https://ncbi.nlm.nih.gov/pubmed/27057434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1069939
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