Signaling through the inhibitory Fc receptor FcγRIIB induces CD8 T cell apoptosis to limit T cell immunity

Effector CD8(+) T cells are important mediators of adaptive immunity, and receptor-ligand interactions that regulate their survival may have therapeutic potential. Here, we identified a subset of effector CD8(+) T cells that expressed the inhibitory Fc receptor FcγRIIB following activation and multi...

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Publicado no:Immunity
Main Authors: Morris, Anna B., Farley, Clara R., Pinelli, David F., Adams, Layne E., Cragg, Mark S., Boss, Jeremy M., Scharer, Christopher D., Fribourg, Miguel, Cravedi, Paolo, Heeger, Peter S., Ford, Mandy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326381/
https://ncbi.nlm.nih.gov/pubmed/31940267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.12.006
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