Signaling through the inhibitory Fc receptor FcγRIIB induces CD8 T cell apoptosis to limit T cell immunity

Effector CD8(+) T cells are important mediators of adaptive immunity, and receptor-ligand interactions that regulate their survival may have therapeutic potential. Here, we identified a subset of effector CD8(+) T cells that expressed the inhibitory Fc receptor FcγRIIB following activation and multi...

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Vydáno v:Immunity
Hlavní autoři: Morris, Anna B., Farley, Clara R., Pinelli, David F., Adams, Layne E., Cragg, Mark S., Boss, Jeremy M., Scharer, Christopher D., Fribourg, Miguel, Cravedi, Paolo, Heeger, Peter S., Ford, Mandy L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326381/
https://ncbi.nlm.nih.gov/pubmed/31940267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.12.006
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