Signaling through the inhibitory Fc receptor FcγRIIB induces CD8 T cell apoptosis to limit T cell immunity

Effector CD8(+) T cells are important mediators of adaptive immunity, and receptor-ligand interactions that regulate their survival may have therapeutic potential. Here, we identified a subset of effector CD8(+) T cells that expressed the inhibitory Fc receptor FcγRIIB following activation and multi...

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Bibliografiske detaljer
Udgivet i:Immunity
Main Authors: Morris, Anna B., Farley, Clara R., Pinelli, David F., Adams, Layne E., Cragg, Mark S., Boss, Jeremy M., Scharer, Christopher D., Fribourg, Miguel, Cravedi, Paolo, Heeger, Peter S., Ford, Mandy L.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326381/
https://ncbi.nlm.nih.gov/pubmed/31940267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.12.006
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