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Engineering Caspase 7 as an Affinity Reagent to Capture Proteolytic Products
Many proteases recognize their substrates with high specificities, with this in mind, it should theoretically be possible to utilize the substrate binding cleft of a protease as a scaffold to engineer an affinity reagent. In this study, we sought to develop reagents that would differentiate between...
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| Publicado no: | FEBS J |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7779697/ https://ncbi.nlm.nih.gov/pubmed/32619291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.15467 |
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