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Engineering Caspase 7 as an Affinity Reagent to Capture Proteolytic Products
Many proteases recognize their substrates with high specificities, with this in mind, it should theoretically be possible to utilize the substrate binding cleft of a protease as a scaffold to engineer an affinity reagent. In this study, we sought to develop reagents that would differentiate between...
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| 出版年: | FEBS J |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7779697/ https://ncbi.nlm.nih.gov/pubmed/32619291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.15467 |
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