OP7, a novel influenza A virus defective interfering particle: production, purification, and animal experiments demonstrating antiviral potential

ABSTRACT: The novel influenza A virus (IAV) defective interfering particle “OP7” inhibits IAV replication in a co-infection and was previously suggested as a promising antiviral agent. Here, we report a batch-mode cell culture-based production process for OP7. In the present study, a seed virus cont...

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Bibliografische gegevens
Gepubliceerd in:Appl Microbiol Biotechnol
Hoofdauteurs: Hein, Marc D., Kollmus, Heike, Marichal-Gallardo, Pavel, Püttker, Sebastian, Benndorf, Dirk, Genzel, Yvonne, Schughart, Klaus, Kupke, Sascha Y., Reichl, Udo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Berlin Heidelberg 2020
Onderwerpen:
Biotechnological Products and Process Engineering
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7778630/
https://ncbi.nlm.nih.gov/pubmed/33275160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-020-11029-5
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