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Production of Defective Interfering Particles of Influenza A Virus in Parallel Continuous Cultures at Two Residence Times—Insights From qPCR Measurements and Viral Dynamics Modeling

Defective interfering particles (DIPs) are a natural byproduct of influenza A virus (IAV) replication. DIPs interfere with the propagation and spread of infectious standard virus (STV), reduce virus yields by competing for viral and cellular resources, and induce antiviral responses. These propertie...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Tapia, Felipe, Laske, Tanja, Wasik, Milena A., Rammhold, Markus, Genzel, Yvonne, Reichl, Udo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813217/
https://ncbi.nlm.nih.gov/pubmed/31681751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00275
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