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Cell culture-based production of defective interfering particles for influenza antiviral therapy

Defective interfering particles (DIPs) lack an essential portion of the virus genome, but retain signals for replication and packaging, and therefore, interfere with standard virus (STV) replication. Due to this property, DIPs can be potential antivirals. The influenza A virus DIP DI244, generated d...

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Détails bibliographiques
Publié dans:Appl Microbiol Biotechnol
Auteurs principaux: Wasik, Milena A., Eichwald, Luca, Genzel, Yvonne, Reichl, Udo
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778153/
https://ncbi.nlm.nih.gov/pubmed/29204901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-017-8660-3
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