Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles

BACKGROUND: Infections with influenza A virus (IAV) cause high morbidity and mortality in humans. Additional to vaccination, antiviral drugs are a treatment option. Besides FDA-approved drugs such as oseltamivir or zanamivir, virus-derived defective interfering (DI) particles (DIPs) are considered p...

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Publicat a:BMC Biol
Autors principals: Hein, Marc D., Arora, Prerna, Marichal-Gallardo, Pavel, Winkler, Michael, Genzel, Yvonne, Pöhlmann, Stefan, Schughart, Klaus, Kupke, Sascha Y., Reichl, Udo
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091782/
https://ncbi.nlm.nih.gov/pubmed/33941189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-021-01020-5
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