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A Novel Type of Influenza A Virus-Derived Defective Interfering Particle with Nucleotide Substitutions in Its Genome

Defective interfering particles (DIPs) replicate at the expense of coinfecting, fully infectious homologous virus. Typically, they contain a highly deleted form of the viral genome. Utilizing single-cell analysis, here we report the discovery of a yet-unknown DIP type, derived from influenza A virus...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kupke, Sascha Young, Riedel, Dietmar, Frensing, Timo, Zmora, Pawel, Reichl, Udo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364022/
https://ncbi.nlm.nih.gov/pubmed/30463972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01786-18
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