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Production of Defective Interfering Particles of Influenza A Virus in Parallel Continuous Cultures at Two Residence Times—Insights From qPCR Measurements and Viral Dynamics Modeling

Defective interfering particles (DIPs) are a natural byproduct of influenza A virus (IAV) replication. DIPs interfere with the propagation and spread of infectious standard virus (STV), reduce virus yields by competing for viral and cellular resources, and induce antiviral responses. These propertie...

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Bibliografiske detaljer
Udgivet i:Front Bioeng Biotechnol
Main Authors: Tapia, Felipe, Laske, Tanja, Wasik, Milena A., Rammhold, Markus, Genzel, Yvonne, Reichl, Udo
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813217/
https://ncbi.nlm.nih.gov/pubmed/31681751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00275
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