Long-Term Gemcitabine Treatment Reshapes the Pancreatic Tumor Microenvironment and Sensitizes Murine Carcinoma to Combination Immunotherapy

Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related death with a median survival time of 6–12 months. Most patients present with disseminated disease and the majority are offered palliative chemotherapy. With no approved treatment modalities for patients who progress on chem...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Principe, Daniel R., Narbutis, Matthew, Kumar, Sandeep, Park, Alex, Viswakarma, Navin, Dorman, Matthew J., Kamath, Suneel D., Grippo, Paul J., Fishel, Melissa L., Hwang, Rosa F., Thummuri, Dinesh, Underwood, Patrick W., Munshi, Hidayatullah G., Trevino, Jose G., Rana, Ajay
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7777391/
https://ncbi.nlm.nih.gov/pubmed/32238357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-2959
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