The Current Treatment Paradigm for Pancreatic Ductal Adenocarcinoma and Barriers to Therapeutic Efficacy

Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis, with a median survival time of 10-12 months. Clinically, these poor outcomes are attributed to several factors, including late stage at the time of diagnosis impeding resectability, as well as multi-drug resistance. Despite the high pre...

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Udgivet i:Front Oncol
Main Authors: Principe, Daniel R., Underwood, Patrick W., Korc, Murray, Trevino, Jose G., Munshi, Hidayatullah G., Rana, Ajay
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319847/
https://ncbi.nlm.nih.gov/pubmed/34336673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.688377
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