Altered Degranulation and pH of Neutrophil Phagosomes Impacts Antimicrobial Efficiency in Cystic Fibrosis

Studies have endeavored to understand the cause for impaired antimicrobial killing by neutrophils of people with cystic fibrosis (PWCF). The aim of this study was to focus on the bacterial phagosome. Possible alterations in degranulation of cytoplasmic granules and changes in pH were assessed. Circu...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Hayes, Elaine, Murphy, Mark P., Pohl, Kerstin, Browne, Niall, McQuillan, Karen, Saw, Le Er, Foley, Clare, Gargoum, Fatma, McElvaney, Oliver J., Hawkins, Padraig, Gunaratnam, Cedric, McElvaney, Noel G., Reeves, Emer P.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775508/
https://ncbi.nlm.nih.gov/pubmed/33391268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.600033
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