Altered Degranulation and pH of Neutrophil Phagosomes Impacts Antimicrobial Efficiency in Cystic Fibrosis

Studies have endeavored to understand the cause for impaired antimicrobial killing by neutrophils of people with cystic fibrosis (PWCF). The aim of this study was to focus on the bacterial phagosome. Possible alterations in degranulation of cytoplasmic granules and changes in pH were assessed. Circu...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hayes, Elaine, Murphy, Mark P., Pohl, Kerstin, Browne, Niall, McQuillan, Karen, Saw, Le Er, Foley, Clare, Gargoum, Fatma, McElvaney, Oliver J., Hawkins, Padraig, Gunaratnam, Cedric, McElvaney, Noel G., Reeves, Emer P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775508/
https://ncbi.nlm.nih.gov/pubmed/33391268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.600033
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