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Targeting IgG Autoantibodies for Improved Cytotoxicity of Bactericidal Permeability Increasing Protein in Cystic Fibrosis

In people with cystic fibrosis (PWCF), inflammation with concurrent infection occurs from a young age and significantly influences lung disease progression. Studies indicate that neutrophils are important effector cells in the pathogenesis of CF and in the development of anti-neutrophil cytoplasmic...

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Autors principals: Karen McQuillan, Fatma Gargoum, Mark P. Murphy, Oliver J. McElvaney, Noel G. McElvaney, Emer P. Reeves
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020-07-01
Col·lecció:Frontiers in Pharmacology
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Accés en línia:https://www.frontiersin.org/article/10.3389/fphar.2020.01098/full
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