KLF4-dependent perivascular plasticity contributes to adipose tissue inflammation

OBJECTIVE: Smooth muscle cells and pericytes (SMC-P) display remarkable plasticity during injury and disease progression. Here, we tested the hypothesis that perivascular cells give rise to Klf4-dependent macrophage (MФ)-like cells that augment adipose tissue inflammation and metabolic dysfunction a...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Bulut, Gamze B., Alencar, Gabriel F., Owsiany, Katherine M., Nguyen, Anh T., Karnewar, Santosh, Haskins, Ryan M., Waller, Lillian K., Cherepanova, Olga A., Deaton, Rebecca A., Shankman, Laura S., Keller, Susanna R., Owens, Gary K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769966/
https://ncbi.nlm.nih.gov/pubmed/33054397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.314703
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