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Klf4 has an unexpected protective role in perivascular cells within the microvasculature
Recent smooth muscle cell (SMC) lineage-tracing studies have revealed that SMCs undergo remarkable changes in phenotype during development of atherosclerosis. Of major interest, we demonstrated that Kruppel-like factor 4 (KLF4) in SMCs is detrimental for overall lesion pathogenesis, in that SMC-spec...
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| 發表在: | Am J Physiol Heart Circ Physiol |
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| Main Authors: | , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6139624/ https://ncbi.nlm.nih.gov/pubmed/29631369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00084.2018 |
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